Preheat your oven to 350°F (175°C).
In a large skillet, heat the olive oil over medium heat. Season the chicken breasts with garlic powder, onion powder, salt, and pepper. Cook the chicken for about 5-7 minutes on each side until golden brown and cooked through. Remove from heat, let it cool slightly, and then cut into bite-sized pieces.
In a mixing bowl, combine the cream of mushroom soup, sour cream, and shredded cheddar cheese. Mix well.
In the prepared baking dish, spread the cooked rice evenly across the bottom. Add the chopped chicken and frozen mixed vegetables, distributing evenly.
Pour the creamy mixture over the chicken and vegetables, spreading it evenly with a spoon.
Sprinkle the crushed potato chips on top for a crunchy texture.
Bake in the preheated oven for 30-35 minutes or until the casserole is bubbling and the top is golden brown.
Once done, remove from the oven and let it cool for a few minutes before serving.