In a mixing bowl, combine the ground beef, salt, black pepper, garlic powder, onion powder, and Worcestershire sauce. Mix gently until fully combined, being careful not to overwork the meat.
Divide the mixture into four equal portions and shape each portion into a patty about ¾ inch thick. Make a slight indentation in the center of each patty to prevent them from puffing up during cooking.
Preheat your grill or stovetop skillet over medium-high heat.
Once hot, place the patties on the grill or skillet and cook for 3-4 minutes on one side without moving them.
Flip the burgers and place a slice of cheddar cheese on each patty. Cook for another 3-4 minutes or until the cheese is melted and the burger reaches your desired doneness (160°F for medium).
While the burgers are cooking, toast the hamburger buns on the grill or in the skillet until golden brown.
Assemble the burgers by placing the cooked patty on the bottom half of each bun. Top with lettuce, tomato slices, and pickles if desired. Spread ketchup and mustard on the top half of the bun and close the burger.
Serve immediately and enjoy your Juicy Crack Burgers!