Preheat your oven to 350°F (175°C).
Carefully take the loaf of brioche and make vertical cuts about 1 inch apart, without cutting all the way through to the bottom. Repeat with horizontal cuts to create a grid pattern.
Slice the brie cheese into small wedges. Place a wedge of brie and a spoonful of cranberry sauce between each cut in the bread.
In a small bowl, mix the melted butter, garlic powder, salt, and black pepper. Brush this mixture generously over the surface of the bread, ensuring it seeps into the cuts.
Wrap the entire loaf in aluminum foil, leaving the top open to avoid steaming.
Place the wrapped bread in the preheated oven and bake for 15 minutes.
After 15 minutes, remove the foil and bake for an additional 15 minutes, or until the bread is golden and the cheese is melted and bubbly.
Once done, remove from the oven and let it cool slightly. Garnish with fresh chopped parsley before serving.
Serve warm, encouraging guests to pull apart the bread and enjoy the melted brie and cranberry sauce.