Preheat the oven to 350°F (175°C).
In a large pot, bring salted water to a boil and cook the egg noodles according to package instructions. Drain the noodles in a colander and set aside.
In a mixing bowl, combine the drained tuna, frozen peas and carrots, cream of mushroom soup, milk, garlic powder, onion powder, and half of the shredded cheddar cheese. Stir until well mixed.
Add the cooked egg noodles to the tuna mixture and fold gently until all ingredients are well incorporated. Season with salt and pepper to taste.
Transfer the mixture into a greased 9x13 inch baking dish, spreading it evenly.
In a separate bowl, mix the breadcrumbs with melted butter and the remaining cheddar cheese. Sprinkle the breadcrumb mixture evenly over the casserole.
Bake in the preheated oven for 25-30 minutes, or until the top is golden and crispy.
Remove from the oven, let it cool for a few minutes, and then serve warm.